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Venlafaxine Hydrochloride

Method: HPLC
Matrix: Medicine
Application No.: 101973
Componds: Venlafaxine Hydrochloride
Columns: Inspire C8 5 μm 150 x 4.6 mm
Cat No.: 81101
Sample Pretreatment: System suitability solution: 0.04mg/mL of venlafaxine hydrochloride in acetonitrile and water (50: 50).
Conditions: Mobile phase: 3.4g of monobasic potassium phosphate in 700mL of water. Adjust with phosphoric acid and water (1: 10) to a pH of 3.0. Make a mixture of acetonitrile and this solution (28: 72).
Detector: UV 225 nm
Flow rate: 1.0 mL/min
Injection size: 10 µL
Column temp.: 30 ℃
Publisher: Dikma Technologies Inc.
Keyword: Venlafaxine Hydrochloride, HPLC, Inspire C8
Abstract: Venlafaxine Hydrochloride is an antidepressant belonging to serotonin and norepinephrine reuptake inhibitor. The experimental conditions follow guidelines from the USP43-NF38 monograph method.

 

Compound

Retention Time

(min)

Tailing Factor

Venlafaxine

Hydrochloride

4.705

1.18